Ovarian, Breast, Prostate and Pancreatic Cancers (PARPi) [DNA, Germline]

Molecular Pathology

02-PARPIG-27

BRCA1 and BRCA2 testing for Ovarian, Breast, prostate and pancreatic cancer (Germline DNA) in the context of PARP inhibitor prescription. This EQA is sponsored.

Sponsored by ,

Overview

The scheme is designed to assess the entire diagnostic pipeline of a laboratory, including sample receipt and processing, analytical processing (genotyping), and reporting (biological and clinical interpretation of the test result) in the context of a clinical referral, as well as reporting clarity, content and clerical accuracy.

At a glance

Product Code:

02-PARPIG-27

Target/Genes:

The scope of this EQA includes testing for variants in the BRCA1 and BRCA2 genes in the germline setting for ovarian, breast, pancreatic and prostate cancers in the context of targeted therapies, such as PARP inhibitors.

Not suitable for laboratories testing for recurrent variants.

Technology:

CNV, MLPA, NGS, Panel testing, Sanger sequencing

Sample Type:

DNA (in TE Buffer)

Submit Results In:

English, French, German, Italian, Spanish

Accredited:

Yes

Key Dates

Register by

28/02/2027

Samples ship

Sep-27

Survey Period

September - November 2027

Final Results

May - June 2028

Sample Details

Three mock clinical cases with matching samples will be provided.

Approximately 2.0µg DNA per sample is provided. Complete information will be available in scheme instructions.

EQA Results

Participants will receive an individual report including educational advice and a scheme report which includes additional information from the cohort of participants including geographical spread, methodologies employed, common errors, learning points and scheme statistics allowing participants to benchmark their results.

Each laboratory will also receive a single certificate listing all EQAs participated in with performance result for each year.

Participation Information

Participants are expected to test samples according to their routine strategy, to return a clinical report with interpretation within the context of targeted PARP inhibitor treatment for the tumour type, and to complete the data collection form.

This EQA is supported by an educational grant from AstraZeneca and MSD, fees are subsidised so there is a reduced cost for participants. The EQA providers acknowledge and thank AstraZeneca and MSD for this support.

The number of participants is restricted, please register early to make sure you don’t miss out.

Open to laboratories from ALL countries (note: some restrictions may apply due to sanctions, delivery network exceptions, restrictions on importation etc).

This EQA is provided in collaboration with GenQA.

Send your enquiry by submitting the form

Closes in 111 days

From £465.00

Buying is completed on the EMQN portal and needs a free EMQN account, which takes a few minutes to set up.

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  • ISO 17043 accredited scheme
  • Submit results in 5 languages

Questions about this scheme?
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