NGS for somatic SNVs and indels – tumour testing only
EQA for quality of NGS for somatic SNVs and indels <50bp (FFPE). For NGS NOT requiring a matched normal control germline sample (single gene, panel testing, whole exome sequencing or whole genome sequencing). Pilot EQA.
Overview
The scheme is designed to assess the analytical process (genotyping) and quality of the raw data.
Please see our DNA SEQUENCING –
NGS (Somatic SNVs and indels + matched germline sample) EQA scheme if you require a matched sample.
At a glance
Product Code:
03-NGSS-SNV-27
Target/Genes:
Any somatic NGS strategy can be used (single gene, panel testing, exome or genome sequencing) that DOES NOT require a matched normal control sample.
The scheme will assess all variants 50bp or less in size. Larger (>50bp in size) changes including copy number and structural variants (CNV’s, SV’s) are covered in a pilot EQA currently in development (please contact
office@emqn.org for more information).
Technology:
NGS, Panel testing, Whole exome sequencing, Whole genome sequencing
Sample Type:
DNA (in TE Buffer)
Submit Results In:
Not applicable
Accredited:
No
Key Dates
01/03/2027
Sep-27
September - November 2027
Sample Details
One mock clinical case and matching tumour DNA sample will be provided.
Approximately 500ng DNA per sample is provided. Complete information will be
available in the scheme instructions.
EQA Results
Participants will receive a comprehensive individual
data quality report and a variant consensus analysis report for each
submission. A comprehensive summary scheme report is provided including
additional information from the cohort of participants including geographical
spread, methodologies employed, common errors, learning points and scheme
statistics allowing participants to benchmark their results.
Each laboratory will also receive a single certificate
listing all EQAs participated in with performance result for each year.
Participation Information
Any somatic NGS strategy can be used (single gene, panel testing, exome or genome sequencing) that DOES NOT require a matched normal control sample.
Participants are expected to test samples according to their routine NGS strategy, to submit VCF, BED, FASTQ and BAM files for analysis.
Laboratories can submit up to three different SNV / indel data sets per participation, derived from different analyses of the EQA sample (e.g. different panels or methodologies).
No restrictions on number of participants. Open to laboratories from ALL countries (note: some restrictions may apply due to sanctions, delivery network exceptions, restrictions on importation etc).
This EQA is provided in collaboration with GenQA.
Send your enquiry by submitting the form
Closes in 112 days
From £770.00
Buying is completed on the EMQN portal and needs a free EMQN account, which takes a few minutes to set up.
Questions about this scheme?
Contact our team
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